2016 : New Prenylated Stilbenes and Antioxidant Activities of Cajanus cajan (L.) Millsp.(Pigeon pea)

Prof. Dr. Taslim Ersam MS.


Abstract

New Prenylated stilbene derivatives, 3-hydroxy-4-prenyl-5-methoxy-stilbene acid (1) and 5, 4'-dihydroxy-3-methoxy-2-prenyl-stilbene (2) had been isolated from methanol extract of Cajanus cajan (L.) Millsp.(Pigeon pea), a member of family fabaceae. The aim of this present work was to evaluate its in vitro antioxidant activity using 2, 2-diphenyl-1-picryhydrazyl (DPPH) radical-scavenging. Isolation of compounds was achieved by extraction (maceration) and chromatographic technique. The structures of the compounds were determined based on UV, IR, 1 H-NMR and 13 C-NMR spectra and also by comparing with the previously reported data. Antioxidant activities (IC 50) of 1 and 2 were 413.68 μg/mL and 271.53 μg/mL, respectively.