Harmin Sulistiyaning Titah : Removal of ibuprofen, ketoprofen, COD and nitrogen compounds from pharmaceutical wastewater using aerobic suspension-sequencing batch reactor (ASSBR).

Harmin Sulistiyaning Titah ST.,MT.,Ph.D.



Published in

Separation and Purification Technology.

External link


Jurnal Internasional


pharmaceutical wastewater; micropollutants; effective microbes; sequencing batch reactor; nitrogen compounds


This study was performed to remove emerging contaminants ibuprofen (IBU) and ketoprofen (KETO), COD and nitrogen compounds from pharmaceutical wastewater. The ASSBR was operated under a constant aeration rate at 1.0 L/min, 24 h HRT and various loadings of IBU (1.715.1 mg/m3 day), KETO (0.392.1 mg/m3 day), COD (1.210 kg/m3 day) and ammonia (NH3N: 4.36.3 g/m3 day). The results showed that IBU, KETO, COD, NH3N and nitrate (NO3N) were efficiently removed in the range of 6390%, 1392%, 88.789.3%, 77.296%, 35.792.5%, respectively. Isolation and screening of effective microbes found three isolates identified as Bacillus pseudomycoides, Rhodococcus ruber and Vibrio mediterranei, which had a higher toxicity resistance towards IBU and KETO. Thus, the pharmaceutical wastewater especially IBU and KETO could be biologically removed with the presents of valuable effective microbes in the ASSBR system.